Acute Trials

Stroke Hyperglycemia Insulin Network Effort (SHINE)

Location: University of Virginia, MedStar Washington Hospital Center,                                      Purpose: The Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial is a multicenter, randomized, controlled clinical trial of 1400 patients that will include approximately 60 enrolling sites. The study hypotheses are that treatment of hyperglycemic acute ischemic stroke patients with targeted glucose concentration (80mg/dL - 130 mg/dL) will be safe and result in improved 3 month outcome after stroke.

Contact: For more information, contact Heather Haughey, 434.243.8065 

Study of Procoagulation Markers in Stroke Patients (I-SPOT)
Location: University of Virginia, MedStar Washington Hospital Center
Purpose: The Insights on Selected Procoagulation Markers and Outcomes in Stroke Trial (I-SPOT): Response to Insulin Administration and Blood Glucose Control proposal is designed to accompany the Stroke Hyperglycemia Insulin Network Effort (SHINE) clinical trial, a Phase III multicenter, randomized, controlled trial planning to determine the efficacy and validate the safety of glycemic control in stroke patients.
Contact: For more information, contact Heather Haughey, 434.243.8065